Efficacy of Aerobic Exercise and a Prudent Diet for Improving Selected Lipids and Lipoproteins in Adults: A Meta-Analysis of Randomized Controlled Trials by
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چکیده
Background: Previous studies addressing the effects of aerobic exercise and a prudent diet on lipids and lipoproteins in adults have reached conflicting conclusions. The purpose of this study was to determine the effects of aerobic exercise combined with a prudent diet on lipids and lipoproteins in adults. Methods: Studies were located by searching nine electronic databases, crossreferencing, and expert review. Two independent reviewers selected studies that met the following criteria: (1) randomized controlled trials, (2) aerobic exercise combined with diet recommendations (saturated/trans fat intake less than 10% of total calories and cholesterol less than 300 mg/day and/or fiber intake > 25 g/day in women and > 35 grams per day in men), (3) intervention lasting at least 4 weeks, (4) adult humans ages 18 years and older, (5) published studies, including dissertations and Master’s theses, (6) studies published in any language, (7) studies published between January 1, 1955 and May 1, 2009, (8) assessment of one or more of the following lipids and lipoproteins: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), ratio of TC to HDLC, non-HDL-C, low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG). Two reviewers independently extracted all data. Random-effects models that account for heterogeneity and 95% confidence intervals were used to pool findings. Results: Of the 1401 citations reviewed, six studies representing 16 groups (8 intervention, 8 control) and up to 559 men and women (282 intervention, 277 control) met the criteria for analysis. Statistically significant intervention minus control reductions were found for TC (-15.5 mg/dl, 95% CI, -20.3 to -10.7), TC:HDL-C (-0.4 mg/dl, 95% CI, -0.7 to -0.2), LDL-C (-9.2 mg/dl, 95% CI, -12.7 to -5.8) and TG (-10.6
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Author's response to reviews Title: Efficacy of Aerobic Exercise and a Prudent Diet for Improving Selected Lipids and Lipoproteins in Adults: A Meta-Analysis of Randomized Controlled Trials Authors:
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Efficacy of aerobic exercise and a prudent diet for improving selected lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials
BACKGROUND Studies addressing the effects of aerobic exercise and a prudent diet on lipid and lipoprotein concentrations in adults have reached conflicting conclusions. The purpose of this study was to determine the effects of aerobic exercise combined with a prudent diet on lipid and lipoprotein concentrations in adults. METHODS Studies were located by searching nine electronic databases, cr...
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